Cheap bus tickets from Osceola to Buffalo
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Osceola to Buffalo Bus Schedule
Bus from Osceola to Buffalo: Journey Information
There are 2 intercity buses per day from Osceola to Buffalo. Traveling by bus from Osceola to Buffalo usually takes around 28 hours and 53 minutes, but the fastest Jefferson Lines bus can make the trip in 24 hours and 10 minutes.
| Distance | 695 mi (1118 km) |
| Shortest duration | 24h 10m |
| Cheapest price | $179.00 |
| Most frequent service | Jefferson Lines |
| Bus lines | 1 |

What bus companies travel from Osceola to Buffalo?
There is one intercity bus company available to search and book on Wanderu that operates from Osceola to Buffalo. Jefferson Lines is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Jefferson Lines | 2 | 1d 4h 53m | $183.50 |
Book Jefferson Lines from Osceola to Buffalo from $179. There are 2 trips per day offered by Jefferson Lines from Osceola to Buffalo and you can expect on average to pay for a Jefferson Lines ticket to Buffalo. In Osceola, Jefferson Lines departs to Buffalo from Pilot Travel Center - 2010 W Clay St . In Buffalo, Jefferson Lines arrives at Buffalo .
An average trip on Jefferson Lines from Osceola to Buffalo takes 28 hours and 53 minutes , while the fastest available Jefferson Lines trip will get you to Buffalo in 24 hours and 10 minutes .
On weekends, Jefferson Lines offers 2 trips per day. A one way ticket costs for a weekend trip to Buffalo.
Frequently asked questions about traveling by bus from Osceola to Buffalo
The bus takes an average of 28 hours and 53 minutes to cover the 695 miles from Osceola to Buffalo. However, the fastest bus only takes 24 hours and 10 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
The first bus leaves at 10:00pm and the last bus leaves at 10:00pm. To see the times for all buses from Osceola to Buffalo, enter your specific travel dates in the search bar.
There are usually only 2 buses per day from Osceola to Buffalo. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.
Need more travel options? Consider taking the train from Osceola, IA to Buffalo, WY; ticket prices start at $221.00.
City Information
Station Information
Where does the bus leave from in Osceola?
Main departure station: Pilot Travel Center - 2010 W Clay St
Most buses depart from the main station in Osceola.
All bus stations in Osceola:
Pilot Travel Center - 2010 W Clay St
Where does the bus arrive in Buffalo?
Main arrival station: Buffalo
All buses from Osceola arrive at one main station in Buffalo.
All bus stations in Buffalo:
Buffalo
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- Osceola, IA to Buffalo, WY






