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St Louis to Durham bus

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St Louis - Durham Bus Schedule

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Journey Information

There are 4 intercity buses per day from St Louis to Durham. Traveling by bus from St Louis to Durham usually takes around 28 hours and 13 minutes, but the fastest Greyhound bus can make the trip in 22 hours and 55 minutes.

Distance647 mi (1041 km)
Shortest duration22h 55m
Cheapest price$141.22
Most frequent serviceGreyhound
Bus lines1

What bus companies travel from St Louis to Durham?

There is one intercity bus company available to search and book on Wanderu that operates from St Louis to Durham. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.

BusDaily TripsAvg. TimeAvg. Price
Greyhound41d 4h 13m$170.09
  • Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 4 bus trips from St Louis to Durham every day, with the average journey taking around 28 hours and 13 minutes to complete. Bus tickets for Greyhound trips to Durham usually start from $141.

Frequently Asked Questions

The bus takes an average of 28 hours and 13 minutes to cover the 647 miles from St Louis to Durham. However, the fastest bus only takes 22 hours and 55 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

The busiest and least busy days to travel on this route tend to change frequently from week to week. Weather, holidays, local events, and other factors can affect how crowded the bus is on any given day.

The first bus leaves at 12:00am and the last bus leaves at 1:00pm. To see the times for all buses from St Louis to Durham, enter your specific travel dates in the search bar.

There are 4 scheduled buses that travel from St Louis to Durham every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey.

City Information

St Louis

St. Louis, MO - STL-0

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St. Louis, MO - STL-1

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St. Louis, MO - STL-2

Image credit: Unsplash

St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.

Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.

Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.

The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.

Durham

Durham is a little treasure cove for all fans of history and the United States’ heritage. The first and foremost thing you should try out is go on a hike on one of the city’s iconic trails. For a more traditional hiking experience, try the Eno River Trail. If you wish to enjoy a more unique experience, the American Tobacco Trail will be a better choice, as it follows the old CSX railroad. For those who want to explore the city’s rich history, check out the Stagville Plantation, which is now a museum dedicated to the city’s antebellum history, offering a unique historical perspective.

Durham’s food scene is vibrant and exciting. Fans of seafood will definitely be amazed at how fresh and delicious the seafood at Mateo Bar de Tapas is. If you wish to try out Italian eats with a twist, check out Devil’s Pizzeria & Restaurant.

The main bus station is the Transportation Center located at 515 W Pettigrew St in Downtown Durham. From there, you can take a bus to New York, Richmond, Washington D.C., and dozens of other destinations across the country. The main Amtrak train station in Durham is located around the corner from the bus stop at 601 W Main St. Durham is served by Amtrak’s Carolinian and Piedmont lines. The city’s air services are handled by the Raleigh-Durham International Airport, 12 miles southeast of the city.

Station Information

Where does the bus leave from in St Louis?

Main departure station: Gateway Station - 430 S 15th St

Most buses depart from the main station in St Louis.

All bus stations in St Louis:

  • Gateway Station - 430 S 15th St

Where does the bus arrive in Durham?

Main arrival station: Durham Transportation Center - Bus Bay T

These are the two stations where buses may stop when they arrive in Durham.

All bus stations in Durham:

  • Durham Transportation Center - Bus Bay T

  • 2918 Guess Rd

Get around town with Moovit

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