Cheap bus tickets from Columbus to Winston-Salem
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Columbus to Winston-Salem Bus Schedule
Bus from Columbus to Winston-Salem: Journey Information
There are 2 intercity buses per day from Columbus to Winston-Salem. Traveling by bus from Columbus to Winston-Salem usually takes around 14 hours and 9 minutes, but the fastest Greyhound bus can make the trip in 9 hours and 25 minutes.
| Distance | 306 mi (492 km) |
| Shortest duration | 9h 25m |
| Cheapest price | $56.98 |
| Trips per day | 1 |
| Most frequent service | Greyhound |
| Bus lines | 2 |

What bus companies travel from Columbus to Winston-Salem?
There are two bus lines that have daily service from Columbus to Winston-Salem that you can compare and book on Wanderu. Of these two carriers, Greyhound usually offers more choice, with 2 scheduled trips per day.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 22h 18m | $237.16 |
| Greyhound | 2 | 14h 0m | $110.99 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Columbus to Winston-Salem, and the average ticket for this route costs only .
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 2 bus trips from Columbus to Winston-Salem every day, with the average journey taking around 14 hours and 0 minutes to complete. Bus tickets for Greyhound trips to Winston-Salem usually start from $57.
Frequently asked questions about traveling by bus from Columbus to Winston-Salem
The bus takes an average of 14 hours and 9 minutes to cover the 306 miles from Columbus to Winston-Salem. However, the fastest bus only takes 9 hours and 25 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Thursday is usually the day of the week when buses are busiest. If you are planning to travel on a Thursday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.
The first bus leaves at 12:00am and the last bus leaves at 9:00pm. To see the times for all buses from Columbus to Winston-Salem, enter your specific travel dates in the search bar.
City Information
Columbus



Brimming with life and cultural events, Columbus is the affordable destination of your dreams! Featuring a budding art scene, Columbus attracts art lovers through the exhibitions at the Columbus Museum of Arts where children and adults alike can indulge in thought-provoking artworks. Fans of sports should not miss out on a baseball game at Huntington Park, which offers reasonably-priced tickets; it is also rarely crowded. For those who simply want to stroll about, the German Village offers a quaint and scenic view rarely seen elsewhere.
As the sun goes down, dig deeper into the German heritage of Columbus by enjoying a traditional schnitzel dish at the Schmidt's Restaurant and Sausage Haus. When you are looking for a quick snack, Bodega serves some of the best sandwiches in town, and there are up to 47 varieties of craft beers for you to choose from.
Columbus’ busiest bus station is located on E Town St., and it offers intercity bus trips to Cleveland, Chicago, New York and many other cities. The Columbus Union Station was the first union station ever built, and it’s served by Amtrak’s Lake Shore Limited and Capitol Limited train lines. The local airport, the John Glenn Columbus International Airport, is located on the east side of the city, 6 miles east of Downtown. It provides access to 31 other airports.
Winston-Salem

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
Ranked as one of the top places to live in the United States, Winston-Salem resulted from the merging of two separate towns in 1913.
The city's oldest and most visually arresting areas are found in what was once simply Salem, a town with a history going back to 1753. You can admire many of the original Moravian-style buildings at Old Salem Museums & Gardens and in the historic districts of West End and Ardmore.
Downtown also has some notable structures, including 100 North Main Street – the tallest office building in the region.
Meanwhile, the main strip when it comes to nightlife is Fourth Street, where bars and restaurants see a steady stream of patrons until long after dark. The presence of no less than six higher education institutions in the city ensures the scene remains fresh and vibrant.
Winston-Salem can be reached from over 175 other U.S. cities. Daily buses depart and arrive from the city's three bus terminals throughout the day, with destinations that include Raleigh, Richmond, and New York City. In addition, Amtrak operates passenger train services via the station at High Point. Its three lines span the region from New York to New Orleans.
Station Information
Where does the bus leave from in Columbus?
Main departure station: Columbus (E Mound St)
Columbus has two bus stations with service to Winston-Salem.
All bus stations in Columbus:
Columbus (E Mound St)
100 E Rich St
Where does the bus arrive in Winston-Salem?

Image credit: Warren LeMay
Link to image attributionMain arrival station: Transp Ctr - 100 W 5th St
The Winston-Salem Transportation Center is on the corner of 5th Street & Trade Street, smack in the middle of the city. It's also commonly called the Greyhound bus station, since the carrier provides a lot of service across North Carolina and its neighboring states. There are plenty of great restaurants in the area, like Butcher & Bull Steakhouse, Downtown Thai & Pho, and Downtown Deli and Cafe, if you want to fill up before your trip. Or, if you want to stretch your legs, Bailey's Park is only a few blocks away and frequently has live music and events.
All bus stations in Winston-Salem:
Transp Ctr - 100 W 5th St
Get around town with Moovit
Need a return trip from Winston-Salem to Columbus?
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