Cheap bus tickets from Pittsburgh to St Louis
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Pittsburgh to St Louis Bus Schedule
Is it better to travel by bus or train from Pittsburgh to St Louis?
There are usually 1 daily train trips available from Pittsburgh to St Louis.
Bus | Train | |
|---|---|---|
Avg. Price | Avg. Price$92.82 | Avg. Price$157.24 |
Daily Trips | Daily Trips3 | Daily Trips1 |
Duration | Duration15h 16m | Duration23h 0m |
Bus from Pittsburgh to St Louis: Journey Information
There are 3 intercity buses per day from Pittsburgh to St Louis. Traveling by bus from Pittsburgh to St Louis usually takes around 14 hours and 4 minutes, but the fastest Greyhound bus can make the trip in 12 hours and 55 minutes.
| Distance | 558 mi (897 km) |
| Shortest duration | 12h 55m |
| Cheapest price | $60.98 |
| Trips per day | 3 |
| Most frequent service | Greyhound |
| Bus lines | 2 |

What bus companies travel from Pittsburgh to St Louis?
There are two bus lines that have daily service from Pittsburgh to St Louis that you can compare and book on Wanderu. Of these two carriers, Greyhound usually offers more choice, with 3 scheduled trips per day.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 20h 55m | $197.97 |
| Greyhound | 3 | 14h 4m | $88.17 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Pittsburgh to St Louis, and the average ticket for this route costs only .
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 3 bus trips from Pittsburgh to St Louis every day, with the average journey taking around 14 hours and 4 minutes to complete. Bus tickets for Greyhound trips to St Louis usually start from $58.
Frequently asked questions about traveling by bus from Pittsburgh to St Louis
The bus takes an average of 14 hours and 4 minutes to cover the 558 miles from Pittsburgh to St Louis. However, the fastest bus only takes 12 hours and 55 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Because many passengers travel from Pittsburgh to St Louis at the beginning of the work week, Monday is usually the busiest day for buses. If you are planning to travel on a Monday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Sunday is typically the least busy day for bus travel on this route. If you are looking for less crowded buses to St Louis, book your ticket for the last day of the week.
The first bus leaves at 1:00am and the last bus leaves at 8:00pm. To see the times for all buses from Pittsburgh to St Louis, enter your specific travel dates in the search bar.
There are 3 scheduled buses that travel from Pittsburgh to St Louis every day, so you have a decent number of options to choose from. Furthermore, all of these are direct buses which you can take the entire route from Pittsburgh to St Louis without transferring.
Need more travel options? Consider taking the train from Pittsburgh to St Louis; ticket prices start at $152.00.
City Information
Pittsburgh



Once the epitome of American industrial power, Pittsburgh has recently seen new waves of changes that turn it into a vibrant destination for visitors, especially for families. When in Pittsburgh, don’t miss out on the chance to hop on the Duquesne Incline and get to the top of Mount Washington. You will be rewarded with a panoramic view of where the three rivers collide, which offers plenty of excellent photogenic angles. Culturally-inclined travelers will find the Senator John Heinz History Center the perfect place to spend a day in. It does not just offer exhibitions on the city’s history but also on its baseball and football legacies, as well as Heinz products. Whether you are a sports fan or not, it is worthwhile to check out the Heinz Field, which provides a unique waterfront view.
Pittsburgh’s staple is pierogies, and some of the highest-rated eateries that include the dish on their menu are Pierogies Plus and Penn Brewery. These establishments serve other Eastern European dishes for your enjoyment as well. For traditional American eats, Eleven has an excellent selection.
Jefferson Lines, Greyhound, and Fullington Trailways all provide intercity transit service to Pittsburgh, and visitors can catch their buses at the Grant Street Transportation Center. You can also catch Amtrak trains at the nearby Pittsburgh Union Station. The main airport of the city is the Pittsburgh International Airport, which is located 10 miles west of Downtown. Another alternative is the Arnold Palmer Regional Airport, 44 miles east of the city.
St Louis

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.
Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.
Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.
The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.
Station Information
Where does the bus leave from in Pittsburgh?

Image credit: An Errant Knight
Link to image attributionMain departure station: Pittsburgh Intermodal/Grant St Trans Ctr
The Grant Street Transportation Center on 11th St is the primary transportation hub of the city. It sits right across the street from the Amtrak Station, and its downtown location makes it convenient to access all of Pittsburgh. The station offers intercity bus services from popular lines such as Greyhound, Fullington Trailways, and Jefferson Lines, with destinations including New York, Philadelphia, and Washington. Ample parking is available at the station, and surrounding amenities include multiple hotels and takeout venues.
All bus stations in Pittsburgh:
Pittsburgh Intermodal/Grant St Trans Ctr
Where does the bus arrive in St Louis?
Main arrival station: Gateway Station - 430 S 15th St
All buses from Pittsburgh arrive at one main station in St Louis.
All bus stations in St Louis:
Gateway Station - 430 S 15th St
Get around town with Moovit
Need a return trip from St Louis to Pittsburgh?
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