Cheap bus tickets from Milwaukee to Spartanburg
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Milwaukee to Spartanburg Bus Schedule
Bus from Milwaukee to Spartanburg: Journey Information
There are 3 intercity buses per day from Milwaukee to Spartanburg. Traveling by bus from Milwaukee to Spartanburg usually takes around 32 hours and 39 minutes, but the fastest FlixBus US bus can make the trip in 27 hours and 35 minutes.
| Distance | 644 mi (1036 km) |
| Shortest duration | 27h 35m |
| Cheapest price | $124.45 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |

What bus companies travel from Milwaukee to Spartanburg?
There is one intercity bus company available to search and book on Wanderu that operates from Milwaukee to Spartanburg. FlixBus US connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 3 | 1d 8h 39m | $192.83 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 3 trips per day from Milwaukee to Spartanburg, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Milwaukee to Spartanburg
The bus takes an average of 32 hours and 39 minutes to cover the 644 miles from Milwaukee to Spartanburg. However, the fastest bus only takes 27 hours and 35 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
With many people traveling in the middle of the week, Wednesday is the busiest day of the week for bus travel. If you are planning to travel on a Wednesday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.
The first bus leaves at 9:00am and the last bus leaves at 3:00pm. To see the times for all buses from Milwaukee to Spartanburg, enter your specific travel dates in the search bar.
There are 3 scheduled buses that travel from Milwaukee to Spartanburg every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey.
Need more travel options? Consider taking the train from Milwaukee to Spartanburg; ticket prices start at $390.00.
City Information
Milwaukee



Nestling on the banks of the great Lake Michigan, Milwaukee has some of the most scenic views around, making it every photographer’s perfect destination. Boasting 85 miles of scenic waterfront bike lanes, Milwaukee is the perfect spot to ride a bike and enjoy the sunset together with your friends. It is also the home of the Harley Davidson Museum, a vast waterfront gallery that offers 11 permanent exhibitions. The museum features not only bikes but also special items such as a whole engine room, making it a must-visit spot for bike enthusiasts. If you are not interested in bikes, the Basilica of St. Josaphat, which is modeled after St. Peter’s Basilica in the Vatican, offers many wondrous shots.
Milwaukee’s famous German bratwursts are a must-try for all visitors, and the best place to enjoy this dish is Usinger’s. Other similar establishments include Mader’s and Milwaukee Public Market. For authentic American eats, Leon's Frozen Custard Drive-In offers amazing sloppy-joe burgers.
The Milwaukee Intermodal Station is the city’s main transportation hub. Visitors can catch both buses and trains at this location. The city is served by two airports. The Milwaukee Mitchell International Airport on the southern edge of the city handles commercial flights, while the Lawrence J. Timmerman Airport in the northwest handles private flights.
Spartanburg

Image credit: Unsplash
Spartanburg is a northern South Carolina city in the Blue Ridge Mountains. Also called The Hub City, it is a major railroad intersection that makes commuting easy. Spartanburg is located close to sandy beaches, high mountains, and the Eastern seaboard, which is ideal for nature lovers. Since it's close to the beach, you can enjoy water activities. Spartanburg offers history in the Spartanburg Regional History Museum, which displays textiles and artifacts, while the Croft State Park is best for fishing enthusiasts. Explore ponds and woodland paths, and go butterfly-watching at the Hatcher Garden.
In the Spartanburg downtown cultural district, you can visit performance venues, galleries, and the Spartanburg Art Museum with an impressive art collection. The city is also home to a vibrant food scene, with local favorites like Cribbs Kitchen and Mon Amie. Spartanburg also features craft breweries and wine bars, with the exciting Spartanburg International Festival held every year.
You can easily get to Spartanburg by bus, with routes offered Tornado Bus and Wanda Coach. There are also train routes to Spartanburg provided by Amtrak and Amtrak Crescent.
Station Information
Where does the bus leave from in Milwaukee?
Main departure station: Mitchell Airport - 5300 S Howell Ave
Milwaukee has two bus stations with service to Spartanburg.
All bus stations in Milwaukee:
Mitchell Airport - 5300 S Howell Ave
Intermodal Station - 433 W ST Paul Ave
Where does the bus arrive in Spartanburg?
Main arrival station: 8671 Asheville Hwy
All buses from Milwaukee arrive at one main station in Spartanburg.
All bus stations in Spartanburg:
8671 Asheville Hwy
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Need a return trip from Spartanburg to Milwaukee?
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