Cheap bus tickets from Cheyenne to Des Moines
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Cheyenne to Des Moines Bus Schedule
Bus from Cheyenne to Des Moines: Journey Information
There is one daily bus from Cheyenne to Des Moines. Traveling by bus from Cheyenne to Des Moines usually takes around 33 hours and 35 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 582 mi (936 km) |
| Shortest duration | 33h 35m |
| Cheapest price | $537.10 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |

What bus companies travel from Cheyenne to Des Moines?
There is one intercity bus company available to search and book on Wanderu that operates from Cheyenne to Des Moines. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 1d 9h 36m | $537.10 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Cheyenne to Des Moines, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Cheyenne to Des Moines
The bus takes an average of 33 hours and 35 minutes to cover the 582 miles from Cheyenne to Des Moines. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
There is usually only one bus per day from Cheyenne to Des Moines. It leaves the station in Cheyenne at 3:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
City Information
Des Moines

Image credit: Unsplash
Des Moines is the capital city of Iowa and the most populous city in the state. It has been named the third-largest insurance capital in the world because of its relevance in the US insurance industry. Des Moines is home to historic landmarks, especially in the East Village area. These include the gold-domed Iowa State Capitol building. Art lovers can visit the Des Moines Art Center, which has notable contemporary collections, and the Pappajohn Sculpture Park, a pedestrian space with public attractions. Des Moines also has spots for outdoor adventures, like the Blank Park Zoo, Greater Des Moines Botanical Garden, and Living History Farms.
Des Moines offers diverse places for entertainment, like the Praire Meadows Casino, Racetrack & Hotel, and the Salisbury House & Gardens, a concert venue in a 1920s manor. In the heart of the city is Downtown Des Moines, which has different attractions and entertainment venues, festivals and concerts, shopping spots, sports teams, restaurants, bars, and breweries.
It's very easy to access Des Moines when you're traveling by bus. Over a hundred neighboring cities offer bus lines to the city, powered by companies like Jefferson Lines, Tornado Bus, Burlington Trailways, and El Expreso Bus. The Des Moines Area Regional Transit Authority also provides bus routes throughout the city.
Station Information
Where does the bus leave from in Cheyenne?
Main departure station: Cheyenne (Sinclair)
Most buses depart from the main station in Cheyenne.
All bus stations in Cheyenne:
Cheyenne (Sinclair)
Where does the bus arrive in Des Moines?
Main arrival station: Bus Station - 1501 2nd St
All buses from Cheyenne arrive at one main station in Des Moines.
All bus stations in Des Moines:
Bus Station - 1501 2nd St
Get around town with Moovit
Need a return trip from Des Moines to Cheyenne?
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- United States
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- Cheyenne to Des Moines






