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Santa Ana to St Louis bus

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Santa Ana - St Louis Bus Schedule

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Journey Information

There are 2 intercity buses per day from Santa Ana to St Louis. Traveling by bus from Santa Ana to St Louis usually takes around 43 hours and 8 minutes, but the fastest FlixBus US bus can make the trip in 43 hours,

Distance1573 mi (2532 km)
Shortest duration43h 0m
Cheapest price$356.46
Most frequent serviceFlixBus US
Bus lines1

What bus companies travel from Santa Ana to St Louis?

There is one intercity bus company available to search and book on Wanderu that operates from Santa Ana to St Louis. FlixBus US is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.

BusDaily TripsAvg. TimeAvg. Price
FlixBus US21d 19h 8m$425.87
  • FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from Santa Ana to St Louis, and the average ticket for this route costs only .

Frequently Asked Questions

The bus takes an average of 43 hours and 8 minutes to cover the 1573 miles from Santa Ana to St Louis. However, the fastest bus only takes 43 hours. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Tuesday is usually the day of the week when buses are busiest. If you are planning to travel on a Tuesday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.

The first bus leaves at 10:00am and the last bus leaves at 10:00am. To see the times for all buses from Santa Ana to St Louis, enter your specific travel dates in the search bar.

There are usually only 2 buses per day from Santa Ana to St Louis. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.

Need more travel options? Consider taking the train from Santa Ana to St Louis; ticket prices start at $240.00.

City Information

Santa Ana

Santa Ana, CA, US - SNA-0

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Santa Ana is a sunny city in Orange County located between Anaheim and Irvine in the greater Los Angeles area. Downtown Santa Ana bustles with independent breweries, diverse restaurants, unique retail shops, weekly pop-up markets, and art centers. This lively downtown area, in addition to Santa Ana's live-work housing and creative working spaces, make it attractive to young professionals.

One of the most popular spots for visitors is the Santa Ana Zoo, where little ones can enjoy a carousel and mini-train ride along with the animal exhibits. Architecture enthusiasts will love seeing the Bowers Museum, built in a Mission Revival style, and the Heritage Museum, which has restored homes from the 1890s.

The Orange County Transportation Authority and several shuttle services provide transit within Santa Ana. Santa Ana is easily accessible from over 20 other cities by Amtrak Thruway bus or on the Amtrak Pacific Surfliner train. The primary airport for Orange County, John Wayne Airport, is located in Santa Ana and also makes it easy to travel to this vibrant SoCal spot.

St Louis

St. Louis, MO - STL-0

Image credit: Unsplash

St. Louis, MO - STL-1

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St. Louis, MO - STL-2

Image credit: Unsplash

St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.

Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.

Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.

The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.

Station Information

Where does the bus leave from in Santa Ana?

Main departure station: Reg Transp Ctr - 1000 E Santa Ana Blvd

Most buses depart from the main station in Santa Ana.

All bus stations in Santa Ana:

  • Reg Transp Ctr - 1000 E Santa Ana Blvd

Where does the bus arrive in St Louis?

Main arrival station: Gateway Station - 430 S 15th St

These are the two stations where buses may stop when they arrive in St Louis.

All bus stations in St Louis:

  • Gateway Station - 430 S 15th St

  • Saint Louis (Lambert Field)

Get around town with Moovit

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Need a return trip from St Louis to Santa Ana?

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