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Key West to San Francisco bus

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Key West - San Francisco Bus Schedule

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Journey Information

There are 2 intercity buses per day from Key West to San Francisco. Traveling by bus from Key West to San Francisco usually takes around 94 hours and 13 minutes, but the fastest FlixBus US bus can make the trip in 93 hours and 40 minutes.

Distance2547 mi (4099 km)
Shortest duration93h 40m
Cheapest price$386.40
Most frequent serviceFlixBus US
Bus lines1

What bus companies travel from Key West to San Francisco?

There is one intercity bus company available to search and book on Wanderu that operates from Key West to San Francisco. FlixBus US is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.

BusDaily TripsAvg. TimeAvg. Price
FlixBus US23d 22h 13m$407.60
  • FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from Key West to San Francisco, and the average ticket for this route costs only .

Frequently Asked Questions

The bus takes an average of 94 hours and 13 minutes to cover the 2547 miles from Key West to San Francisco. However, the fastest bus only takes 93 hours and 40 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

The busiest and least busy days to travel on this route tend to change frequently from week to week. Weather, holidays, local events, and other factors can affect how crowded the bus is on any given day.

The first bus leaves at 12:00pm and the last bus leaves at 12:00pm. To see the times for all buses from Key West to San Francisco, enter your specific travel dates in the search bar.

There are usually only 2 buses per day from Key West to San Francisco. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.

City Information

Key West

Key West, FL - KWT-0

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Key West, FL - KWT-1

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Key West, FL - KWT-2

Image credit: Unsplash

Key West is the southernmost city in the contiguous U.S. and a popular tourist destination in Florida. Known for its abundance of sea wildlife, Key West is a fantastic place for you to book a boat tour and enjoy the Gulf of Mexico's coral reefs. Tours also offer unique opportunities like dolphin watching, snorkeling, and much more. For the best beach around, head toward the Fort Zachary Taylor Historic State Park, where you can sunbathe and fish with ease. The Key West Butterfly & Nature Conservatory is a magical spot to learn more about different butterfly variations.

Seafood is still the staple of Key West's cuisine, but the distinct Caribbean and Cuban touch will set the city's food scene apart from others. For the best authentic Cuban specialties, try El Siboney. If you enjoy classic Floridan dishes, Blue Heaven will not disappoint you.

Although Key West is an island city on the Florida Keys archipelago, the Overseas Highway connects to the mainland. This means you can easily catch a bus directly to Key West. Domestic and international flights go through the centrally-located Key West International Airport.

San Francisco

San Francisco, CA - SFO-0

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San Francisco, CA - SFO-1

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San Francisco, CA - SFO-2

Image credit: Unsplash

Located in the heart of Northern California's Bay Area, San Francisco is a geographically small but culturally huge city known for its historic cable cars, active waterfront, and the eclectic mix of hippies and techies who call it home. While it might be one of the most expensive U.S. cities to live in, San Fran can actually be very cheap to visit, and there is no shortage of unique sights to see.

If the city's omnipresent fog (nicknamed "Karl the Fog" by locals) takes a break, the best views and Instagram photo ops of the world-famous Golden Gate Bridge are found in Golden Gate Park. Stroll through the oldest Chinatown in North America to find the perfect dim sum, or if you and your boo prefer a little Full House moment, try a romantic picnic at Alamo Square Park in front of the Victorian "Painted Ladies." After all, San Francisco is one of the best vacation destinations for couples.

Since the city is condensed onto a small peninsula, exploring by bike is an efficient and scenic way to get around. When you’re ready to travel beyond city limits, San Francisco is a convenient hub for trips throughout Northern California. It's actually the first stop on Wanderu's West Coast Wine Tour, with the next stop, obviously, in Napa Valley. Whether traveling by bus, train, or through either of the two nearby airports, San Francisco is a can't-miss destination.

Station Information

Where does the bus leave from in Key West?

Main departure station: 908 Caroline St, between Grinnell and Margaret Sts

Most buses depart from the main station in Key West.

All bus stations in Key West:

  • 908 Caroline St, between Grinnell and Margaret Sts

Where does the bus arrive in San Francisco?

Main arrival station: Caltrain Station - 5th & Townsend St

These are the two stations where buses may stop when they arrive in San Francisco.

All bus stations in San Francisco:

  • Caltrain Station - 5th & Townsend St

  • Salesforce Transit Center

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