Cheap bus tickets from Indianapolis to Key West
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Indianapolis to Key West Bus Schedule
Bus from Indianapolis to Key West: Journey Information
There is one daily bus from Indianapolis to Key West. Traveling by bus from Indianapolis to Key West usually takes around 34 hours and 2 minutes, but the fastest FlixBus US bus can make the trip in 33 hours,
| Distance | 1081 mi (1740 km) |
| Shortest duration | 33h 0m |
| Cheapest price | $145.95 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |

What bus companies travel from Indianapolis to Key West?
There is one intercity bus company available to search and book on Wanderu that operates from Indianapolis to Key West. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 1d 10h 2m | $213.47 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Indianapolis to Key West, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Indianapolis to Key West
The bus takes an average of 34 hours and 2 minutes to cover the 1081 miles from Indianapolis to Key West. However, the fastest bus only takes 33 hours. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Thursday is usually the day of the week when buses are busiest. If you are planning to travel on a Thursday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Sunday is typically the least busy day for bus travel on this route. If you are looking for less crowded buses to Key West, book your ticket for the last day of the week.
There is usually only one bus per day from Indianapolis to Key West. It leaves the station in Indianapolis at 11:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
City Information
Indianapolis



Indianapolis, or often referred to as just Indy, is the capital and largest city in the state of Indiana. While the city attracts thousands of visitors from the area every month, it is during Memorial Day weekend that Indianapolis becomes the place to be for over 300,000 race car fans from all over the globe. The reason for that is the Indianapolis 500, an annual automobile race and the world’s largest single day sporting event, taking place at the iconic Indianapolis Motor Speedway.
If you’re not in Indianapolis for Memorial Day weekend, you can learn about the race and see a rare collection of 500 Indy race vehicles and memorabilia at the Indianapolis Motor Speedway Museum. And while you’re on a history streak, stop by at one of the many war memorials found throughout the city, like the Soldiers and Sailors monument, the World War II memorial, and the Indiana War Memorial where you must check out the Shrine Room for a stunning one-of-a-kind experience.
Over the past few years, Indianapolis has also been cultivating a vibrant restaurant scene, offering classic American dishes made with ingredients from local farmers, and a growing selection of international cuisine. If you’re a beer fan, you will be happy to know that Indianapolis has some of the highest quality breweries in the U.S.
Located in the heart of America’s Midwest, Indianapolis offers easy connections by bus and train to other Midwestern hubs like Chicago, Louisville, and Cincinnati, while the conveniently located airport connects Indy with the rest of the world.
Key West

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
Key West is the southernmost city in the contiguous U.S. and a popular tourist destination in Florida. Known for its abundance of sea wildlife, Key West is a fantastic place for you to book a boat tour and enjoy the Gulf of Mexico's coral reefs. Tours also offer unique opportunities like dolphin watching, snorkeling, and much more. For the best beach around, head toward the Fort Zachary Taylor Historic State Park, where you can sunbathe and fish with ease. The Key West Butterfly & Nature Conservatory is a magical spot to learn more about different butterfly variations.
Seafood is still the staple of Key West's cuisine, but the distinct Caribbean and Cuban touch will set the city's food scene apart from others. For the best authentic Cuban specialties, try El Siboney. If you enjoy classic Floridan dishes, Blue Heaven will not disappoint you.
Although Key West is an island city on the Florida Keys archipelago, the Overseas Highway connects to the mainland. This means you can easily catch a bus directly to Key West. Domestic and international flights go through the centrally-located Key West International Airport.
Station Information
Where does the bus leave from in Indianapolis?
Main departure station: E Washington St
Most buses depart from the main station in Indianapolis.
All bus stations in Indianapolis:
E Washington St
Where does the bus arrive in Key West?
Main arrival station: Ky West Bus Station
All buses from Indianapolis arrive at one main station in Key West.
All bus stations in Key West:
Ky West Bus Station
Get around town with Moovit
Need a return trip from Key West to Indianapolis?
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