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Buses from Knoxville to Columbus

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Knoxville - Columbus Bus Schedule

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Journey Information

There are 2 intercity buses per day from Knoxville to Columbus. Traveling by bus from Knoxville to Columbus usually takes around 11 hours and 59 minutes, but the fastest Greyhound bus can make the trip in 9 hours and 45 minutes.

Distance281 mi (452 km)
Shortest duration9h 45m
Cheapest price$52.00
Most frequent serviceGreyhound
Bus lines1

Price trends for buses from Knoxville to Columbus

Average prices by travel date

$75$50$25MayJun

Monthly average prices

$100$80$60$40$20JJASONDJFMAM

What bus companies travel from Knoxville to Columbus?

There is one intercity bus company available to search and book on Wanderu that operates from Knoxville to Columbus. Greyhound is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.

BusDaily TripsAvg. TimeAvg. Price
Greyhound211h 59m$63.38
  • Greyhound

    Greyhound

    Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 2 bus trips from Knoxville to Columbus every day, with the average journey taking around 11 hours and 59 minutes to complete. Bus tickets for Greyhound trips to Columbus usually start from $52.

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Frequently Asked Questions

Is it safe to travel by bus from Knoxville to Columbus during the COVID-19 pandemic?

Our bus partners have implemented several different policies to keep you safe during the COVID-19 pandemic. From limiting vehicle capacity to enhancing cleaning protocols and upgrading air filters, bus carriers are committed to maintaining a safe environment. For details on what each company is doing to ensure their fleet remains safe for travel, click here.

Although masks are no longer required on public transportation, we stand behind CDC guidelines that encourage passengers to wear a mask over their nose and mouth while on the bus or in stations.

Please visit our COVID-19 Travel Guide for more information on all carrier policies and the latest travel advisories issued by every U.S. state, Canadian province, and European country.

How long is the bus ride from Knoxville to Columbus?

The bus takes an average of 11 hours and 59 minutes to cover the 281 miles from Knoxville to Columbus. However, the fastest bus only takes 9 hours and 45 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

What is the busiest day of the week to travel by bus?

Thursday is usually the day of the week when buses are busiest. If you are planning to travel on a Thursday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Sunday is typically the least busy day for bus travel on this route. If you are looking for less crowded buses to Columbus, book your ticket for the last day of the week.

When do the earliest and latest buses leave Knoxville?

The first bus leaves at 10:00pm and the last bus leaves at 11:00pm. To see the times for all buses from Knoxville to Columbus, enter your specific travel dates in the search bar.

How many bus departures serve Columbus each day?

There are usually only 2 buses per day from Knoxville to Columbus. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.

City Information

Columbus

Brimming with life and cultural events, Columbus is the affordable destination of your dreams! Featuring a budding art scene, Columbus attracts art lovers through the exhibitions at the Columbus Museum of Arts where children and adults alike can indulge in thought-provoking artworks. Fans of sports should not miss out on a baseball game at Huntington Park, which offers reasonably-priced tickets; it is also rarely crowded. For those who simply want to stroll about, the German Village offers a quaint and scenic view rarely seen elsewhere.

As the sun goes down, dig deeper into the German heritage of Columbus by enjoying a traditional schnitzel dish at the Schmidt's Restaurant and Sausage Haus. When you are looking for a quick snack, Bodega serves some of the best sandwiches in town, and there are up to 47 varieties of craft beers for you to choose from.

Columbus’ busiest bus station is located on E Town St., and it offers intercity bus trips to Cleveland, Chicago, New York and many other cities. The Columbus Union Station was the first union station ever built, and it’s served by Amtrak’s Lake Shore Limited and Capitol Limited train lines. The local airport, the John Glenn Columbus International Airport, is located on the east side of the city, 6 miles east of Downtown. It provides access to 31 other airports.

Station Information

Where does the bus leave from in Knoxville?

Main departure station: Marathon Gas

Most buses depart from the main station in Knoxville.

All bus stations in Knoxville:

  • Marathon Gas

Where does the bus arrive in Columbus?

Bus Terminal - 111 E Town St  - CMHGLI2-0

Image credit: Antony-22

Link to image attribution

Main arrival station: Columbus, Ohio

The Bus Terminal at 111 E Town St is Columbus’ hub for intercity bus service on a variety of carriers including Jefferson Lines, Greyhound, Miller Transportation, Barons Bus Lines, and Amtrak Thruway. Conveniently located in downtown Columbus, the station’s area features several parking lots, hotels, and fast food restaurants. The waiting area within the station building includes restrooms, vending machines, and even arcade-style games if you’re prone to boredom while waiting for the bus. From this station, you can travel to destinations including Cincinnati, Chicago, and New York.

All bus stations in Columbus:

  • Columbus, Ohio

Need a return trip from Columbus to Knoxville?

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