|Shortest Duration||7h 35m|
|Trips per day||3|
Book Greyhound from Knoxville to Columbus from $52.00. There are 3 trips per day offered by Greyhound from Knoxville to Columbus and you can expect on average to pay $70.97 for a Greyhound ticket to Columbus. In Knoxville, Greyhound departs to Columbus from Bus Terminal - 100 E Magnolia Ave, In Columbus, Greyhound arrives at Bus Terminal - 111 E Town St and 2 other stations.
An average trip on Greyhound from Knoxville to Columbus takes 8 hours and 33 minutes, while the fastest available Greyhound trip will get you to Columbus in 7 hours and 35 minutes,
On weekends, Greyhound offers 3 trips per day. A one way ticket costs $63.91 for a weekend trip to Columbus.