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San Antonio to Key West bus

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San Antonio - Key West Bus Schedule

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Journey Information

There is one daily bus from San Antonio to Key West. Traveling by bus from San Antonio to Key West usually takes around 61 hours and 5 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.

Distance1081 mi (1740 km)
Shortest duration61h 5m
Cheapest price$231.95
Most frequent serviceFlixBus US
Bus lines1

What bus companies travel from San Antonio to Key West?

There is one intercity bus company available to search and book on Wanderu that operates from San Antonio to Key West. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.

BusDaily TripsAvg. TimeAvg. Price
FlixBus US12d 13h 5m$231.95
  • FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from San Antonio to Key West, and the average ticket for this route costs only .

Frequently Asked Questions

The bus takes an average of 61 hours and 5 minutes to cover the 1081 miles from San Antonio to Key West. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

The busiest and least busy days to travel on this route tend to change frequently from week to week. Weather, holidays, local events, and other factors can affect how crowded the bus is on any given day.

There is usually only one bus per day from San Antonio to Key West. It leaves the station in San Antonio at 9:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.

There is usually only one bus per day from San Antonio to Key West. However, it is not a direct bus, so you will have to get off your original vehicle to change buses during the trip.

City Information

San Antonio

San Antonio, TX - SAT-0

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San Antonio, TX - SAT-1

Image credit: Unsplash

San Antonio, TX - SAT-2

Image credit: Unsplash

San Antonio is a fast-growing city located in the southwest corner of the Texas Triangle. In addition to the alluring year-round warm weather, San Antonio offers a blend of rich history with contemporary attractions and cuisine.

If there's one thing to remember from your trip to San Antonio, it’s the Alamo! This 18th century fortress is one of five Spanish missions in the San Antonio Missions National Historical Park, all of which are connected by a scenic hiking and biking trail. If history isn't your thing, the River Walk along the San Antonio River is a much livelier spot. This shaded path is lined with shops and restaurants, and you could spend an entire day strolling, shopping, and eating along the river. Don't sleep on the riverside bars, either – San Antonio is one of the cheapest drinking cities in the U.S. so you can bar-hop to your heart’s (and your wallet’s) delight.

Traveling with little ones? San Antonio is home to the San Antonio Zoo, SeaWorld, and Six Flags Fiesta Texas, any one of which will provide a thrilling adventure with no screen time required. Visitors of all ages will find treasures at Historic Market Square, the largest Mexican market in the U.S., where handcrafted art from local artisans is available alongside authentic Mexican food.

San Antonio is one of the biggest cities in the Lone Star State, so it is very easy to travel to other Texas destinations like Austin, Houston, and Dallas by bus or by train, or to destinations farther afield through the San Antonio International Airport.

Key West

Key West, FL - KWT-0

Image credit: Unsplash

Key West, FL - KWT-1

Image credit: Unsplash

Key West, FL - KWT-2

Image credit: Unsplash

Key West is the southernmost city in the contiguous U.S. and a popular tourist destination in Florida. Known for its abundance of sea wildlife, Key West is a fantastic place for you to book a boat tour and enjoy the Gulf of Mexico's coral reefs. Tours also offer unique opportunities like dolphin watching, snorkeling, and much more. For the best beach around, head toward the Fort Zachary Taylor Historic State Park, where you can sunbathe and fish with ease. The Key West Butterfly & Nature Conservatory is a magical spot to learn more about different butterfly variations.

Seafood is still the staple of Key West's cuisine, but the distinct Caribbean and Cuban touch will set the city's food scene apart from others. For the best authentic Cuban specialties, try El Siboney. If you enjoy classic Floridan dishes, Blue Heaven will not disappoint you.

Although Key West is an island city on the Florida Keys archipelago, the Overseas Highway connects to the mainland. This means you can easily catch a bus directly to Key West. Domestic and international flights go through the centrally-located Key West International Airport.

Station Information

Where does the bus leave from in San Antonio?

Bus Terminal - 500 N St Marys St - SATGLI-0

Image credit: Paul Sableman

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Main departure station: Bus Terminal - 500 N St Marys St

The San Antonio Bus Terminal on St. Mary’s Street is open 24 hours a day, and welcomes travelers on Jefferson Lines and Greyhound bus trips throughout Texas and beyond. Just a stone’s throw from the San Antonio River in downtown, the bus station offers connections to local transit via nearby public bus stops and ample parking for those who’d like to leave their car in a lot or garage. Fresh food can be purchased in the station, or stop by any one of the nearby cafes and restaurants for a bite before your trip.

All bus stations in San Antonio:

  • Bus Terminal - 500 N St Marys St

Where does the bus arrive in Key West?

Main arrival station: 908 Caroline St, between Grinnell and Margaret Sts

All buses from San Antonio arrive at one main station in Key West.

All bus stations in Key West:

  • 908 Caroline St, between Grinnell and Margaret Sts

Get around town with Moovit

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Need a return trip from Key West to San Antonio?

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