Cheap bus tickets from Enterprise to San Diego
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Bus from Enterprise to San Diego: Journey Information
There are 23 intercity buses per day from Enterprise to San Diego. Traveling by bus from Enterprise to San Diego usually takes around 8 hours and 49 minutes, but the fastest Las Vegas Shuttles bus can make the trip in 6 hours and 2 minutes.
- Distance
- 253 mi (408 km)
- Shortest duration
- 6h 2m
- Cheapest price
- $34.98
- Trips per day
- 23
- Most frequent service
- Greyhound
- Bus lines
- 2
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Enterprise to San Diego Bus Schedule

There are several bus options that can take you from Enterprise to San Diego:
See more detailsHow much is a bus ticket from Enterprise to San Diego?
Bus tickets for a trip from Enterprise to San Diego cost about $66 when you book at the cheapest time, 22 days ahead. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Enterprise to San Diego by travel date
If you're planning to travel by bus from Enterprise to San Diego in the next month, the average ticket price is expected to range from $61 to $89. The cheapest bus tickets available in the next few weeks are for trips departing on November 16, 2026. If you’re looking to travel to San Diego this week, bus tickets are available starting at $71.
Average bus ticket prices from Enterprise to San Diego by month
Taking the bus from Enterprise to San Diego is usually cheapest in August, when the average ticket price is only $71. If you're planning to take the bus from Enterprise to San Diego during May, keep in mind that bus ticket prices may be higher than usual, with an average price of $83. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 22 days in advance. This way, you can save up to $30.25 on your bus ticket compared to booking last-minute.
What bus companies travel from Enterprise to San Diego?
There are two bus lines that have daily service from Enterprise to San Diego that you can compare and book on Wanderu. Of these two carriers, Greyhound usually offers more choice, with 18 scheduled trips per day.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 18 | 10h 7m | $76.62 |
| Las Vegas Shuttles | 6 | 6h 13m | $88.98 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 18 bus trips from Enterprise to San Diego every day, with the average journey taking around 10 hours and 7 minutes to complete. Bus tickets for Greyhound trips to San Diego usually start from $34.98.






Book Las Vegas Shuttles from Enterprise to San Diego from $87. There are 6 trips per day offered by Las Vegas Shuttles from Enterprise to San Diego and you can expect on average to pay $88.98 for a Las Vegas Shuttles ticket to San Diego. In Enterprise, Las Vegas Shuttles departs to San Diego from Las Vegas Dean Martin Blue Diamond. In San Diego, Las Vegas Shuttles arrives at 4055 University Ave and one other station.
An average trip on Las Vegas Shuttles from Enterprise to San Diego takes 6 hours and 13 minutes, while the fastest available Las Vegas Shuttles trip will get you to San Diego in 6 hours and 2 minutes.
On weekends, Las Vegas Shuttles offers 7 trips per day. A one way ticket costs $87 for a weekend trip to San Diego.
Frequently asked questions about traveling by bus from Enterprise to San Diego
There are 23 scheduled buses that travel from Enterprise to San Diego every day, so you have a decent number of options to choose from. This includes 8 direct buses, where you can stay on the same bus without having to transfer to a connecting bus at any point during your trip. Need more travel options? Consider taking the train from Enterprise to San Diego; ticket prices start at $140.
Trips per day
23
Direct trips
8
The bus takes an average of 8 hours and 49 minutes to cover the 253 miles from Enterprise to San Diego. However, the fastest bus only takes 6 hours and 2 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
253
Distance (km)
408
The first bus leaves at 2:30 AM and the last bus leaves at 11:45 PM. To see the times for all buses from Enterprise to San Diego, enter your specific travel dates in the search bar.
Earliest bus
2:30am
Latest bus
11:45pm
Friday is the busiest travel day for buses as people head from Enterprise to San Diego for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.
Most crowded
Friday
Least crowded
Thursday
City Information
San Diego



San Diego is known as “America's Finest City” for its sunny weather, white-sand beaches, and dazzling attractions from Belmont Park to SeaWorld. San Diego's 70 miles of pristine beaches include such gems as Mission Beach, Pacific Beach, La Jolla Cove, and Coronado Beach. The city's strong surfing culture may even inspire you to rent a surfboard and catch the epic waves, bro.
Visitors can spend days getting lost in Balboa Park, a 1,200-acre cultural hub which features 16 museums, immaculate gardens, and the world-famous San Diego Zoo. The historic heart of the city, Old Town, showcases San Diego's heritage and ties to Mexican culture, while other sights like the USS Midway pay tribute to the city's military and maritime history. Leave time for some evening exploring, too! San Diego is rated the #1 best city for craft beer in America, so don't miss out on the bars in the Gaslamp Quarter: 16 walkable blocks packed with nightlife and young crowds.
Two airports, as well as many bus and train options, mean it is easy to get to San Diego from afar or from nearby cities like Tijuana, Los Angeles, Phoenix, and Las Vegas.
Station Information
Where does the bus leave from in Enterprise?
Main departure station: South Strip Transfer Terminal

The South Strip Transfer Terminal is the main bus station in Las Vegas. It is conveniently located near the world-famous Las Vegas Strip, making it easy to get between the station and all major Vegas resorts. The bus station is also in very close proximity to Harry Reid International Airport, and there’s a transit bus line that connects the two. The South Strip Transfer Terminal is the main bus station for all major bus companies that conduct trips in and out of Las Vegas, including Greyhound, Jefferson Lines and Tufesa Internacional. The terminal is the main hub for RTC, Southern Nevada’s transit bus authority, ensuring easy connections to all parts of Las Vegas and its surrounding areas.
All bus stations in Enterprise:
- South Strip
- Las Vegas Dean Martin Blue Diamond
Where does the bus arrive in San Diego?
Main arrival station: San Ysidro Transit Center
Buses arrive in San Diego at 7 stations, depending on which bus line you are traveling with.
All bus stations in San Diego:
- San Ysidro Transit Center
- San Ysidro Bus Terminal
- La Jolla - UC San Diego
- 2728 Congress St (Old Town SD)
- 4055 University Ave
- 789 W Harbor Dr - Seaport Village
Need a return trip from San Diego to Enterprise?
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