Cheap bus tickets from Florence to Winston-Salem
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Florence to Winston-Salem Bus Schedule
Bus from Florence to Winston-Salem: Journey Information
There is one daily bus from Florence to Winston-Salem. Traveling by bus from Florence to Winston-Salem usually takes around 6 hours and 40 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 134 mi (216 km) |
| Shortest duration | 6h 40m |
| Cheapest price | $74.47 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |

What bus companies travel from Florence to Winston-Salem?
There is one intercity bus company available to search and book on Wanderu that operates from Florence to Winston-Salem. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 6h 41m | $101.98 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Florence to Winston-Salem, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Florence to Winston-Salem
The bus takes an average of 6 hours and 40 minutes to cover the 134 miles from Florence to Winston-Salem. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
With many people traveling in the middle of the week, Wednesday is the busiest day of the week for bus travel. If you are planning to travel on a Wednesday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Saturday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Saturday ticket is the way to go.
There is usually only one bus per day from Florence to Winston-Salem. It leaves the station in Florence at 12:00am each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
There is usually only one bus per day from Florence to Winston-Salem. However, it is not a direct bus, so you will have to get off your original vehicle to change buses during the trip.
Need more travel options? Consider taking the train from Florence, SC to Winston-Salem, NC; ticket prices start at $84.50.
City Information
Florence
Florence is a hidden gem in the northeast of South Carolina. Though best known for its history as a significant railway hub, Florence is a modern city with activities and sights to fill a weekend getaway or a longer vacation.
Every November, Florence goes nuts during the SC Pecan Music and Food Festival, an event hosted downtown to celebrate the beloved pecan. If you're in town during the festival, check out the car show, live music, half marathon, and other associated events to get to know Florence locals and culture.
Florence is a year-round destination for outdoor recreation. Golf is a favorite among Florence residents, so upgrade from mini-golf and try the real thing. Traces Golf Club welcomes golfers of all skill levels, don't worry. Don't leave Florence without spending a day at Lynches River County Park, the starting point of the 66-mile South Carolina Revolutionary Rivers Trail. You can kayak or canoe throughout the county, following the swampy path that allowed American patriots to evade British troops in the American Revolution.
Florence Regional Airport operates limited flights to connect to Charlotte, but most paths to Florence involve some kind of ground travel. Amtrak's Palmetto and Silver Service trains stop in Florence, with connections to New York and Washington to the north and Orlando and Miami to the south. Greyhound and Southeastern Stages offer intercity bus service to Florence that connects the city to other destinations throughout the South.
Winston-Salem

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
Ranked as one of the top places to live in the United States, Winston-Salem resulted from the merging of two separate towns in 1913.
The city's oldest and most visually arresting areas are found in what was once simply Salem, a town with a history going back to 1753. You can admire many of the original Moravian-style buildings at Old Salem Museums & Gardens and in the historic districts of West End and Ardmore.
Downtown also has some notable structures, including 100 North Main Street – the tallest office building in the region.
Meanwhile, the main strip when it comes to nightlife is Fourth Street, where bars and restaurants see a steady stream of patrons until long after dark. The presence of no less than six higher education institutions in the city ensures the scene remains fresh and vibrant.
Winston-Salem can be reached from over 175 other U.S. cities. Daily buses depart and arrive from the city's three bus terminals throughout the day, with destinations that include Raleigh, Richmond, and New York City. In addition, Amtrak operates passenger train services via the station at High Point. Its three lines span the region from New York to New Orleans.
Station Information
Where does the bus leave from in Florence?
Main departure station: 2301 W Lucas St (TA Gas Station)
Most buses depart from the main station in Florence.
All bus stations in Florence:
2301 W Lucas St (TA Gas Station)
Where does the bus arrive in Winston-Salem?

Image credit: Warren LeMay
Link to image attributionMain arrival station: Transp Ctr - 100 W 5th St
The Winston-Salem Transportation Center is on the corner of 5th Street & Trade Street, smack in the middle of the city. It's also commonly called the Greyhound bus station, since the carrier provides a lot of service across North Carolina and its neighboring states. There are plenty of great restaurants in the area, like Butcher & Bull Steakhouse, Downtown Thai & Pho, and Downtown Deli and Cafe, if you want to fill up before your trip. Or, if you want to stretch your legs, Bailey's Park is only a few blocks away and frequently has live music and events.
All bus stations in Winston-Salem:
Transp Ctr - 100 W 5th St
Get around town with Moovit
Need a return trip from Winston-Salem to Florence?
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