Buses from Chicago to St Louis

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Chicago - St Louis Bus Schedule

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Journey Information

There are 4 intercity buses per day from Chicago to St Louis. Traveling by bus from Chicago to St Louis usually takes around 8 hours and 11 minutes, but the fastest Greyhound bus can make the trip in 6 hours and 15 minutes.

Distance262 mi (422 km)
Shortest duration6h 15m
Cheapest price$33.00
Trips per day2
Most frequent serviceGreyhound
Bus lines2

Bus Trip Reviews from Wanderu Customers

Overall score for buses from Chicago to St Louis

(Based on 6 ratings and reviews)

4.3

2.0

Chaoyue

July 7, 2019- Solo travel

Greyhound

Air conditioner is leaking water to the seats

Air conditioner is leaking water to the seats

How much is a bus ticket from Chicago to St Louis?

$34.00 is the average price of a bus ticket from Chicago to St Louis. Taking a bus is an affordable way to make this trip. It’s easy to find a bus ticket at this price or lower when you use Wanderu to book your trip online in advance of your travel date.

Average prices by travel date

$45$30$15AugAug

Over the next four weeks, the average ticket price of a bus from Chicago to St Louis is expected to range from $33 to $39. If you are looking to travel to St Louis within the next week, you can find bus tickets starting from $34. The cheapest bus tickets in the next month are $33 and can be found on August 30, 2022.

Monthly average prices

$50$40$30$20$10SONDJFMAMJJA

The lowest bus ticket prices on this route can usually be found in May. That’s when the average price of a bus ticket is expected to be just $39 – the lowest of the year.

Alternatively, if you plan to travel from Chicago to St Louis in January, expect to spend more on your bus trip, as the average ticket price may surge to $45 at that time of year. However, if you book your trip ahead of time, you can still score a ticket at a lower price.

Prices as travel date approaches

$100$80$60$40$203020100

Most bus companies charge higher ticket prices the closer you book to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. The best way to find cheap bus tickets is to book at least 29 days in advance. By doing so, you can expect to save $21.83 on your bus ticket compared to booking at the last minute.

What bus companies travel from Chicago to St Louis?

There are two bus lines that have daily service from Chicago to St Louis that you can compare and book on Wanderu. Of these two carriers, Greyhound usually offers more choice, with 4 scheduled trips per day.

BusDaily TripsAvg. TimeAvg. Price
Burlington Trailways110h 30m$84.80
Greyhound48h 11m$37.59
  • Burlington Trailways

    Burlington Trailways

    As part of the Trailways network, Burlington Trailways offers intercity bus service across various states in the Midwest, plus stops in major cities like Chicago and Denver. Passengers love traveling on Trailways buses because of the high-end amenities onboard, including satellite TV, power outlets at every seat, and clean restrooms. Burlington Trailways is also known for the best free Wi-Fi and its helpful, friendly crew.

  • Greyhound

    Greyhound

    Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 4 bus trips from Chicago to St Louis every day, with the average journey taking around 8 hours and 11 minutes to complete. Bus tickets for Greyhound trips to St Louis usually start from $33.

Frequently Asked Questions

Is there a train from Chicago to St. Louis?

Yes, the Amtrak runs from Chicago to St. Louis. Both the Amtrak Texas Eagle and Amtrak Lincoln Service cover this route.

However, the bus may be a better option. Both the train and the bus take as little as just over 5 hours to reach St. Louis, but bus tickets cost $22 on average, whereas train tickets cost closer to $30. Plus, while there are only 5 daily train trips for this route, there are 15 daily bus trips, so it may be easier to find a bus trip that fits your schedule.

Does Megabus go to St. Louis from Chicago?

Yes, Megabus does go to St. Louis from Chicago. Megabus offers 1 trip per day for this route, and tickets cost about $25 on average.

What is the cheapest bus from Chicago to St. Louis?

The cheapest bus from Chicago to St. Louis is usually Greyhound, with an average price of about $24.50 per ticket. Greyhound also offers the most daily trips for this route.

Is it safe to travel by bus from Chicago to St Louis during the COVID-19 pandemic?

Our bus partners have implemented several different policies to keep you safe during the COVID-19 pandemic. From limiting vehicle capacity to enhancing cleaning protocols and upgrading air filters, bus carriers are committed to maintaining a safe environment. For details on what each company is doing to ensure their fleet remains safe for travel, click here.

Although masks are no longer required on public transportation, we stand behind CDC guidelines that encourage passengers to wear a mask over their nose and mouth while on the bus or in stations.

Please visit our COVID-19 Travel Guide for more information on all carrier policies and the latest travel advisories issued by every U.S. state, Canadian province, and European country.

How long is the bus ride from Chicago to St Louis?

The bus takes an average of 8 hours and 11 minutes to cover the 262 miles from Chicago to St Louis. However, the fastest bus only takes 6 hours and 15 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

What is the busiest day of the week to travel by bus?

Buses from Chicago to St Louis are the most crowded on Monday. Tickets also tend to be more expensive then. If you are looking for a great deal on your bus tickets or just want extra room to stretch out, consider traveling on Sunday instead, as it tends to be the least crowded day of the week.

When do the earliest and latest buses leave Chicago?

The first bus leaves at 6:00am and the last bus leaves at 10:00pm. To see the times for all buses from Chicago to St Louis, enter your specific travel dates in the search bar.

How many buses are there each day?

There are 4 scheduled buses that travel from Chicago to St Louis every day, so you have a decent number of options to choose from. This includes 2 direct buses, where you can stay on the same bus without having to transfer to a connecting bus at any point during your trip.

Need more travel options? Consider taking the train from Chicago to St Louis; ticket prices start at $25.00.

City Information

Chicago

Known for its innovative architecture, cultural contributions to jazz and house music, and of course that irresistible deep-dish pizza, the many sights and experiences in Chicago make it one of the best urban vacation destinations for millennials and a top destination in Illinois.

You can't beat the views of the city and Lake Michigan from the SkyDeck in the Willis Tower; at over 1,300 feet, this is the highest observation deck in the U.S. Snap that classic selfie with the Bean in Millennium Park, then wander the many museums in nearby Grant Park. Navy Pier is a popular tourist hotspot for its parks, restaurants, and attractions right on Lake Michigan, and baseball fans will find paradise in Wrigleyville, home to the Chicago Cubs' Wrigley Field and sports bars galore.

Chicago's enormous parks offer plentiful opportunities for outdoor activities in gorgeous urban settings. Many companies offer kayak rentals or boat tours on the Chicago River, with special tours running on Saint Patrick's Day, when the entire river is dyed green. When you’re ready to buy some souvenirs from your epic trip, hit the big brand stores on the Magnificent Mile, or shop local in neighborhoods like Andersonville and Wicker Park. And don't miss the chance to laugh until you cry at The Second City comedy theater, famous for launching the careers of comedians like Tina Fey and Stephen Colbert.

Chicago is one of the biggest transportation hubs in the Midwest, and provides easy access to nearby destinations ideal for day trips, as well as international travel from two airports. Thanks to plenty of bus and train stations throughout the city, getting to the Windy City is a breeze.

St Louis

St. Louis, MO - STL-2

Image credit: Unsplash

St. Louis, MO - STL-0

Image credit: Unsplash

St. Louis, MO - STL-1

Image credit: Unsplash

St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.

Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.

Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.

The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.

Station Information

Where does the bus leave from in Chicago?

Main departure station: Bus Station - 630 W Harrison St

Most buses depart from the main station in Chicago.

All bus stations in Chicago:

  • Bus Station - 630 W Harrison St

Where does the bus arrive in St Louis?

Gateway Station - 430 S 15th St - STLAMT-0

Image credit: Chris Yunker

Link to image attribution

Main arrival station: Gateway Station - 430 S 15th St

Gateway Station opened in 2008 to consolidate St Louis’ transportation services into one central hub. The station’s award-winning design includes a pedestrian walkway with expansive colored glass windows overlooking the train tracks. Perfectly located in the heart of downtown St Louis, the station is surrounded by bars, restaurants, and hotels and is just a few blocks from Busch Stadium and the iconic Gateway Arch. Amenities inside the station include free Wifi, a food court, and a lounge for Amtrak’s First Class passengers. Gateway Station is a major stop for intercity bus service, several Amtrak train lines, and the city’s MetroLink which can connect you with the St Louis Lambert International Airport in just 30 minutes.

All bus stations in St Louis:

  • Gateway Station - 430 S 15th St

Need a return trip from St Louis to Chicago?

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