COVID-19 Travel Guide
Learn more ›

Find bus tickets from Chicago to St Louis

Lowest PricesWe work directly with hundreds of bus & train carriers to find the best available fares.
No Wanderu FeesWe never add any extra fees. We just make it easy to book your bus & train tickets.
Best Travel OptionsWe help you find & compare the best buses and trains in one place.

Journey Information

Chicago to St Louis bus - cost & duration

Cheapest price$25.00
Shortest Duration6h 15m
Trips per day13
Bus lines1

Frequently Asked Questions

Is there a train from Chicago to St. Louis?

Yes, the Amtrak runs from Chicago to St. Louis. Both the Amtrak Texas Eagle and Amtrak Lincoln Service cover this route.

However, the bus may be a better option. Both the train and the bus take as little as just over 5 hours to reach St. Louis, but bus tickets cost $22 on average, whereas train tickets cost closer to $30. Plus, while there are only 5 daily train trips for this route, there are 15 daily bus trips, so it may be easier to find a bus trip that fits your schedule.

Does Megabus go to St. Louis from Chicago?

Yes, Megabus does go to St. Louis from Chicago. Megabus offers 1 trip per day for this route, and tickets cost about $25 on average.

What is the cheapest bus from Chicago to St. Louis?

The cheapest bus from Chicago to St. Louis is usually Greyhound, with an average price of about $24.50 per ticket. Greyhound also offers the most daily trips for this route.

Is it safe to travel by bus from Chicago to St Louis right now?

We stand behind CDC guidelines that caution passengers against non-essential travel during the coronavirus outbreak. That said, we recognize not everyone is in a position to completely abstain. Whether it’s for work, to take care of family or to get back home, some circumstances inevitably require travel. If you’re one of those individuals who still needs to book a trip, you can continue to do so on Wanderu.

Know that most bus companies are still running at this time, though some have limited service. Visit our COVID-19 travel guide for resources and daily updates on the coronavirus and COVID travel restrictions.

In order to keep vehicles as clean and sanitized as possible, bus companies are taking extra precautions for coronavirus. For details on what various companies are doing to ensure their fleet remains safe for travel, click here.

How much is a bus ticket from Chicago to St Louis?

Based on daily average prices in last 30 days, $28.35 was the low point for bus fares from Chicago to St Louis. Buses from St Louis to Chicago are similarly priced. Any tickets cheaper than $28.35 could be considered a great deal.

The best way to find cheap deals on bus tickets is by booking as early as possible, since most bus companies increase the price as the travel date approaches. You should book at least 14 days in advance. By doing so, you could save $25.31 on your ticket compared to booking at the last minute.

How long is the bus ride?

The bus usually takes around 11 hours and 24 minutes to cover the 262 miles (422 kilometers) from Chicago, IL to St Louis, MO. However, the fastest bus only takes 6 hours and 15 minutes. The trip is definitely on the longer side, so plan to get comfortable on the bus. It's a good idea to bring water and snacks.

What is the busiest day of the week to travel by bus?

Sunday tends to be the busiest day for buses, as many passengers take the bus to St Louis at the end of the week. If you are planning to travel on a Sunday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.

When do the earliest and latest buses leave Chicago?

The first bus leaves at 1:00am and the last bus leaves at 10:00pm. To see the times for all buses from Chicago to St Louis, enter your specific travel dates in the search bar.

How many buses are there each day?

There are 13 scheduled buses that travel from Chicago to St Louis every day, so you have a decent number of options to choose from. This includes 2 direct buses, where you can stay on the same bus without having to transfer to a connecting bus at any point during your trip.

Need more travel options? Consider taking the train from Chicago to St Louis; ticket prices start at $25.00.

What bus companies travel from Chicago to St Louis?

There is one bus company that operates from Chicago to St Louis. Greyhound is the only company that connects the two cities by bus. Fortunately, it has multiple scheduled buses per day, so travelers still have a good amount of choice and flexibility.

BusDaily TripsAvg. TimeAvg. Price
Greyhound1311h 24m$35.28

Where does the bus leave from in Chicago?

Buses to St Louis leave from multiple locations in Chicago, Illinois. These are the 4 most popular bus stations:

  • Dan Ryan Bus Station
  • Bus Station - 630 W Harrison St
  • 5800 N Cumberland Ave
  • Union Station - 225 S Canal St

Where does the bus arrive in St Louis?

These are the two stations where buses may stop when they arrive in St Louis, Missouri:

  • Gateway Station - 430 S 15th St
  • Lambert Intl Apt Busport

Price trends for buses from Chicago to St Louis

Average prices by travel date


Monthly average prices


Prices as travel date approaches


Bus Trip Reviews from Wanderu Customers

Overall score for buses from Chicago, IL to St Louis, MO

(Based on 6 ratings and reviews)




July 7, 2019 - Solo travel


Air conditioner is leaking water to the seatsAir conditioner is leaking water to the seats

Book buses and trains on the go with the Wanderu app.

Download our app and snag the best travel deals across North America & Europe.Learn more

Available on iOS & Android