Cheap bus tickets from La Crosse to Indianapolis
Find and compare the best ground travel options in one place.
Millions of travelers trust Wanderu every year to get:
Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 500+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
See what travelers are saying about Wanderu:
La Crosse to Indianapolis Bus Schedule
Bus from La Crosse to Indianapolis: Journey Information
There are 2 intercity buses per day from La Crosse to Indianapolis. Traveling by bus from La Crosse to Indianapolis usually takes around 30 hours and 11 minutes, but the fastest Jefferson Lines bus can make the trip in 30 hours,
| Distance | 382 mi (615 km) |
| Shortest duration | 30h 0m |
| Cheapest price | $179.00 |
| Most frequent service | Jefferson Lines |
| Bus lines | 1 |
What bus companies travel from La Crosse to Indianapolis?
There is one intercity bus company available to search and book on Wanderu that operates from La Crosse to Indianapolis. Jefferson Lines is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Jefferson Lines | 2 | 1d 6h 11m | $179.00 |
Book Jefferson Lines from La Crosse to Indianapolis from $179. There are 2 trips per day offered by Jefferson Lines from La Crosse to Indianapolis and you can expect on average to pay for a Jefferson Lines ticket to Indianapolis. In La Crosse, Jefferson Lines departs to Indianapolis from 314 Jay St and one other station. In Indianapolis, Jefferson Lines arrives at 350 S Illinois St .
An average trip on Jefferson Lines from La Crosse to Indianapolis takes 30 hours and 11 minutes , while the fastest available Jefferson Lines trip will get you to Indianapolis in 30 hours and 0 minutes .
Frequently asked questions about traveling by bus from La Crosse to Indianapolis
The bus takes an average of 30 hours and 11 minutes to cover the 382 miles from La Crosse to Indianapolis. However, the fastest bus only takes 30 hours. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Tuesday is usually the day of the week when buses are busiest. If you are planning to travel on a Tuesday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.
The first bus leaves at 12:00pm and the last bus leaves at 12:00pm. To see the times for all buses from La Crosse to Indianapolis, enter your specific travel dates in the search bar.
There are usually only 2 buses per day from La Crosse to Indianapolis. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.
Need more travel options? Consider taking the train from La Crosse to Indianapolis; ticket prices start at $102.00.
City Information
La Crosse
A busy college town blessed with lush and beautiful green zones, La Crosse is one of the best places to just chill out and unwind. The city's star attraction is the Grandad Bluff, which offers a panoramic view of the entire city and the Mississippi River. Hiking up the hill will certainly be a challenge, but the view from the top makes it all worthwhile. While staying in the city, don't miss out on the chance to go on a cruise aboard the La Crosse Queen, a replica paddle steamer, and unwind while enjoying the sunset. For some family fun, head over to the Children's Museum of La Crosse.
La Crosse does have a pretty reputable food scene, with a strong focus on beers and cheese curds. For an upscale dining experience with the best local dishes, The Waterfront Restaurant & Tavern is a local favorite that has a stellar reputation. Or head to the Dublin Square Irish Pub & Eatery for a combination of good foods and drinks.
La Crosse is easily accessible by bus or train, and regional flights operate out of the La Crosse Municipal Airport.
Indianapolis
Indianapolis, or often referred to as just Indy, is the capital and largest city in the state of Indiana. While the city attracts thousands of visitors from the area every month, it is during Memorial Day weekend that Indianapolis becomes the place to be for over 300,000 race car fans from all over the globe. The reason for that is the Indianapolis 500, an annual automobile race and the world’s largest single day sporting event, taking place at the iconic Indianapolis Motor Speedway.
If you’re not in Indianapolis for Memorial Day weekend, you can learn about the race and see a rare collection of 500 Indy race vehicles and memorabilia at the Indianapolis Motor Speedway Museum. And while you’re on a history streak, stop by at one of the many war memorials found throughout the city, like the Soldiers and Sailors monument, the World War II memorial, and the Indiana War Memorial where you must check out the Shrine Room for a stunning one-of-a-kind experience.
Over the past few years, Indianapolis has also been cultivating a vibrant restaurant scene, offering classic American dishes made with ingredients from local farmers, and a growing selection of international cuisine. If you’re a beer fan, you will be happy to know that Indianapolis has some of the highest quality breweries in the U.S.
Located in the heart of America’s Midwest, Indianapolis offers easy connections by bus and train to other Midwestern hubs like Chicago, Louisville, and Cincinnati, while the conveniently located airport connects Indy with the rest of the world.
Station Information
Where does the bus leave from in La Crosse?
Main departure station: 314 Jay St
Buses to La Crosse stop at Jay Street in front of the Grand River Station. The aptly-named grand building features arching ceilings, marble decoration, and amenities like seating and vending machines inside. The station is conveniently located in downtown La Crosse with easy access to surrounding hotels, restaurants, and a rental car agency across the street. Bus lines, including Greyhound and Jefferson Lines, connect La Crosse to Minneapolis, Milwaukee, Chicago, and beyond.
All bus stations in La Crosse:
314 Jay St
University of WI
Where does the bus arrive in Indianapolis?
Image credit: Panoramio upload bot
Link to image attributionMain arrival station: 350 S Illinois St
Union Station at 350 S Illinois St in Indianapolis is a major train and bus station which serves the Amtrak Cardinal, and bus carriers including Greyhound, Jefferson Lines, Miller Transportation, and Burlington Trailways. The modern station is located directly south of the historic 1888 Union Station, which now houses a hotel, several restaurants, and a wedding venue. Union Station is in the Wholesale District of downtown Indianapolis, within walking distance to eateries and hotels. There is even an underground, climate-controlled walkway from the station to the nearby Indiana Convention Center and Lucas Oil Stadium, home to the Indianapolis Colts.
All bus stations in Indianapolis:
350 S Illinois St
Get around town with Moovit
Need a return trip from Indianapolis to La Crosse?
Search Bus Tickets
Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.