|Shortest Duration||18h 0m|
|Trips per day||5|
Book Amtrak from Indianapolis to Depew from $108.00. There are 5 Amtrak schedules from Indianapolis to Depew and you can expect on average to pay $108.00 for a Amtrak ticket to Depew. In Indianapolis, Amtrak departs to Depew from 350 S Illinois St and no other station. In Depew, Amtrak arrives at 55 Dick Rd and no other station.
An average trip on Amtrak from Indianapolis to Depew takes 21 hours and 23 minutes, while the fastest available Amtrak trip will get you to Depew in 18 hours and 0 minutes,