background-img-buses-trains
chiku-desktop

Cheap bus tickets from San Francisco to Santa Ana

Find and compare the best ground travel options in one place.

chiku-mobile

Millions of travelers trust Wanderu every year to get:

Lowest Prices

We find the cheapest bus & train tickets, so you can wander for less.

Best Travel Options

We partner with 500+ carriers to bring you the most bus & train options.

Quick & Easy Booking

Book trips quickly with a simple, hassle-free checkout – online & on our app.

Fast Customer Support

We don’t monkey around. We respond within minutes to help you out.

See what travelers are saying about Wanderu:

Download our free app!

Find, compare & book buses and trains on the go with the Wanderu app.

4.8 Rating

5k Reviews

4.5 Rating

4.8k Reviews

Chiku

San Francisco to Santa Ana Bus Schedule

Find cheap rental carsFind great deals on cheap cars in the area.
RentalCars logotypeRentalCars logotype
from$30.00

Is it better to travel by bus or train from San Francisco to Santa Ana?

There are usually 4 daily train trips available from San Francisco to Santa Ana.

Bus
Train
Avg. Price
Avg. Price
$53.52
Avg. Price
$63.22
Daily Trips
Daily Trips
5
Daily Trips
4
Duration
Duration
13h 13m
Duration
12h 19m

Bus from San Francisco to Santa Ana: Journey Information

There are 6 intercity buses per day from San Francisco to Santa Ana. Traveling by bus from San Francisco to Santa Ana usually takes around 13 hours and 37 minutes, but the fastest FlixBus US bus can make the trip in 10 hours and 5 minutes.

Distance378 mi (608 km)
Shortest duration10h 5m
Cheapest price$34.97
Trips per day1
Most frequent serviceGreyhound
Bus lines2

Wander into savings:
Get deals in your inbox!

Sign up to get the latest deals on bus & train tickets sent directly to you.

How much is a bus ticket from San Francisco to Santa Ana?

Bus tickets for a trip from San Francisco to Santa Ana cost $50.96 on average. Tickets cheaper than $50.96 are an excellent bargain. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.

Average bus ticket prices from San Francisco to Santa Ana by travel date

$105$70$35JanJan

If you're planning to travel by bus from San Francisco to Santa Ana in the next month, the average ticket price is expected to range from $48 to $97. The cheapest bus tickets available in the next few weeks are for trips departing on January 14, 2025.

If you’re looking to travel to Santa Ana this week, bus tickets are available starting at $48.

Prices as travel date approaches

$125$100$75$50$253020100

Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 28 days in advance. This way, you can save up to $71.13 on your bus ticket compared to booking last-minute.

What bus companies travel from San Francisco to Santa Ana?

There are two bus lines that have daily service from San Francisco to Santa Ana that you can compare and book on Wanderu. Of these two carriers, Greyhound usually offers more choice, with 3 scheduled trips per day.

BusDaily TripsAvg. TimeAvg. Price
FlixBus US312h 11m$91.27
Greyhound314h 5m$76.64
  • FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 3 trips per day from San Francisco to Santa Ana, and the average ticket for this route costs only .

  • Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 3 bus trips from San Francisco to Santa Ana every day, with the average journey taking around 14 hours and 5 minutes to complete. Bus tickets for Greyhound trips to Santa Ana usually start from $35.

Frequently asked questions about traveling by bus from San Francisco to Santa Ana

The bus takes an average of 13 hours and 37 minutes to cover the 378 miles from San Francisco to Santa Ana. However, the fastest bus only takes 10 hours and 5 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Sunday tends to be the busiest day for buses, as many passengers take the bus to Santa Ana at the end of the week. If you are planning to travel on a Sunday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.

The first bus leaves at 6:00am and the last bus leaves at 11:00pm. To see the times for all buses from San Francisco to Santa Ana, enter your specific travel dates in the search bar.

There are 6 scheduled buses that travel from San Francisco to Santa Ana every day, so you have a decent number of options to choose from. However, only one of these is a direct bus. With direct service, you do not have to transfer onto a different bus at any point during your trip. Direct buses also tend to be significantly faster, which is worth bearing in mind as you compare the available options.

Need more travel options? Consider taking the train from San Francisco to Santa Ana; ticket prices start at $57.00.

City Information

San Francisco

San Francisco, CA - SFO-0

Image credit: Unsplash

San Francisco, CA - SFO-1

Image credit: Unsplash

San Francisco, CA - SFO-2

Image credit: Unsplash

Located in the heart of Northern California's Bay Area, San Francisco is a geographically small but culturally huge city known for its historic cable cars, active waterfront, and the eclectic mix of hippies and techies who call it home. While it might be one of the most expensive U.S. cities to live in, San Fran can actually be very cheap to visit, and there is no shortage of unique sights to see.

If the city's omnipresent fog (nicknamed "Karl the Fog" by locals) takes a break, the best views and Instagram photo ops of the world-famous Golden Gate Bridge are found in Golden Gate Park. Stroll through the oldest Chinatown in North America to find the perfect dim sum, or if you and your boo prefer a little Full House moment, try a romantic picnic at Alamo Square Park in front of the Victorian "Painted Ladies." After all, San Francisco is one of the best vacation destinations for couples.

Since the city is condensed onto a small peninsula, exploring by bike is an efficient and scenic way to get around. When you’re ready to travel beyond city limits, San Francisco is a convenient hub for trips throughout Northern California. It's actually the first stop on Wanderu's West Coast Wine Tour, with the next stop, obviously, in Napa Valley. Whether traveling by bus, train, or through either of the two nearby airports, San Francisco is a can't-miss destination.

Santa Ana

Santa Ana, CA, US - SNA-0

Image credit: Unsplash

Santa Ana is a sunny city in Orange County located between Anaheim and Irvine in the greater Los Angeles area. Downtown Santa Ana bustles with independent breweries, diverse restaurants, unique retail shops, weekly pop-up markets, and art centers. This lively downtown area, in addition to Santa Ana's live-work housing and creative working spaces, make it attractive to young professionals.

One of the most popular spots for visitors is the Santa Ana Zoo, where little ones can enjoy a carousel and mini-train ride along with the animal exhibits. Architecture enthusiasts will love seeing the Bowers Museum, built in a Mission Revival style, and the Heritage Museum, which has restored homes from the 1890s.

The Orange County Transportation Authority and several shuttle services provide transit within Santa Ana. Santa Ana is easily accessible from over 20 other cities by Amtrak Thruway bus or on the Amtrak Pacific Surfliner train. The primary airport for Orange County, John Wayne Airport, is located in Santa Ana and also makes it easy to travel to this vibrant SoCal spot.

Station Information

Where does the bus leave from in San Francisco?

Main departure station: Salesforce Transit Center

Buses to Santa Ana leave from 3 stations in San Francisco.

All bus stations in San Francisco:

  • Salesforce Transit Center

  • Caltrain Station - 5th & Townsend St

  • 700 Beach Street

Where does the bus arrive in Santa Ana?

Main arrival station: Reg Transp Ctr - 1000 E Santa Ana Blvd

All buses from San Francisco arrive at one main station in Santa Ana.

All bus stations in Santa Ana:

  • Reg Transp Ctr - 1000 E Santa Ana Blvd

Get around town with Moovit

Find the best way to get to and from any station in Santa Ana by public transit, courtesy of Moovit. Search now

Need a return trip from Santa Ana to San Francisco?

Search Bus Tickets

Wanderu is the simplest way to book bus and train travel.

With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.