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Buses from Indianapolis to St Louis

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Indianapolis - St Louis Bus Schedule

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Journey Information

There are 3 intercity buses per day from Indianapolis to St Louis. Traveling by bus from Indianapolis to St Louis usually takes around 4 hours and 25 minutes, but the fastest Greyhound bus can make the trip in 3 hours and 55 minutes.

Distance230 mi (371 km)
Shortest duration3h 55m
Cheapest price$61.00
Trips per day3
Most frequent serviceGreyhound
Bus lines2

Bus Trip Reviews from Wanderu Customers

Overall score for buses from Indianapolis to St Louis

(Based on 2 ratings and reviews)

5.0

5.0

Cheryl Ann

March 18, 2022- Visiting family

Greyhound

Pros: Very direct - easy to schedule and loved the WI/FI- watched a movie!! Cons: The seat did not adjust - headrest uncomfortable and the charging dock not working at my seat. Tips: Would use Greyhound again.

Pros: Very direct - easy to schedule and loved the WI/FI- watched a movie!! Cons: The seat did not adjust - headrest uncomfortable and the charging dock not working at my seat. Tips: Would use Greyhound again.

How much is a bus ticket from Indianapolis to St Louis?

$73.36 is the average price of a bus ticket from Indianapolis to St Louis. While it’s on the pricier side for a bus ticket, taking the bus is still a cheaper alternative to flying. It’s easy to find a bus ticket at this price or lower when you use Wanderu to book your trip online in advance of your travel date.

Average prices by travel date

$90$60$30MayJun

Over the next four weeks, the average ticket price of a bus from Indianapolis to St Louis is expected to range from $73 to $90. If you are looking to travel to St Louis within the next week, you can find bus tickets starting from $75. The cheapest bus tickets in the next month are $73 and can be found on June 15, 2022.

Monthly average prices

$100$80$60$40$20JJASONDJFMAM

The lowest bus ticket prices on this route can usually be found in May. That’s when the average price of a bus ticket is expected to be just $61 – the lowest of the year.

Alternatively, if you plan to travel from Indianapolis to St Louis in October, expect to spend more on your bus trip, as the average ticket price may surge to $78 at that time of year. However, if you book your trip ahead of time, you can still score a ticket at a lower price.

Prices as travel date approaches

$100$80$60$40$203020100

Most bus companies charge higher ticket prices the closer you book to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. The best way to find cheap bus tickets is to book at least 27 days in advance. By doing so, you can expect to save $30.24 on your bus ticket compared to booking at the last minute.

What bus companies travel from Indianapolis to St Louis?

There are two bus lines that have daily service from Indianapolis to St Louis that you can compare and book on Wanderu. Of these two carriers, Greyhound usually offers more choice, with 3 scheduled trips per day.

BusDaily TripsAvg. TimeAvg. Price
Burlington Trailways111h 5m$102.00
Greyhound34h 26m$83.04
  • Burlington Trailways

    Burlington Trailways

    As part of the Trailways network, Burlington Trailways offers intercity bus service across various states in the Midwest, plus stops in major cities like Chicago and Denver. Passengers love traveling on Trailways buses because of the high-end amenities onboard, including satellite TV, power outlets at every seat, and clean restrooms. Burlington Trailways is also known for the best free Wi-Fi and its helpful, friendly crew.

  • Greyhound

    Greyhound

    Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 3 bus trips from Indianapolis to St Louis every day, with the average journey taking around 4 hours and 26 minutes to complete. Bus tickets for Greyhound trips to St Louis usually start from $61.

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Frequently Asked Questions

Is it safe to travel by bus from Indianapolis to St Louis during the COVID-19 pandemic?

Our bus partners have implemented several different policies to keep you safe during the COVID-19 pandemic. From limiting vehicle capacity to enhancing cleaning protocols and upgrading air filters, bus carriers are committed to maintaining a safe environment. For details on what each company is doing to ensure their fleet remains safe for travel, click here.

Although masks are no longer required on public transportation, we stand behind CDC guidelines that encourage passengers to wear a mask over their nose and mouth while on the bus or in stations.

Please visit our COVID-19 Travel Guide for more information on all carrier policies and the latest travel advisories issued by every U.S. state, Canadian province, and European country.

How long is the bus ride from Indianapolis to St Louis?

The bus takes an average of 4 hours and 25 minutes to cover the 230 miles from Indianapolis to St Louis. However, the fastest bus only takes 3 hours and 55 minutes. In other words, you'll have plenty of time to rest and relax on the road. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

What is the busiest day of the week to travel by bus?

Thursday is usually the day of the week when buses are busiest. If you are planning to travel on a Thursday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Sunday is typically the least busy day for bus travel on this route. If you are looking for less crowded buses to St Louis, book your ticket for the last day of the week.

When do the earliest and latest buses leave Indianapolis?

The first bus leaves at 3:00am and the last bus leaves at 8:00pm. To see the times for all buses from Indianapolis to St Louis, enter your specific travel dates in the search bar.

How many buses are there each day?

There are 3 scheduled buses that travel from Indianapolis to St Louis every day, so you have a decent number of options to choose from. Furthermore, all of these are direct buses which you can take the entire route from Indianapolis to St Louis without transferring.

Need more travel options? Consider taking the train from Indianapolis to St Louis; ticket prices start at $48.00.

City Information

Indianapolis

Indianapolis, or often referred to as just Indy, is the capital and largest city in the state of Indiana. While the city attracts thousands of visitors from the area every month, it is during Memorial Day weekend that Indianapolis becomes the place to be for over 300,000 race car fans from all over the globe. The reason for that is the Indianapolis 500, an annual automobile race and the world’s largest single day sporting event, taking place at the iconic Indianapolis Motor Speedway.

If you’re not in Indianapolis for Memorial Day weekend, you can learn about the race and see a rare collection of 500 Indy race vehicles and memorabilia at the Indianapolis Motor Speedway Museum. And while you’re on a history streak, stop by at one of the many war memorials found throughout the city, like the Soldiers and Sailors monument, the World War II memorial, and the Indiana War Memorial where you must check out the Shrine Room for a stunning one-of-a-kind experience.

Over the past few years, Indianapolis has also been cultivating a vibrant restaurant scene, offering classic American dishes made with ingredients from local farmers, and a growing selection of international cuisine. If you’re a beer fan, you will be happy to know that Indianapolis has some of the highest quality breweries in the U.S.

Located in the heart of America’s Midwest, Indianapolis offers easy connections by bus and train to other Midwestern hubs like Chicago, Louisville, and Cincinnati, while the conveniently located airport connects Indy with the rest of the world.

St Louis

St. Louis, MO - STL-0

Image credit: Unsplash

St. Louis, MO - STL-1

Image credit: Unsplash

St. Louis, MO - STL-2

Image credit: Unsplash

St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.

Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.

Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.

The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.

Station Information

Where does the bus leave from in Indianapolis?

Indianapolis, IN - Indianapolis Union Station (350 S Illinois St) - INDAMT-0

Image credit: Panoramio upload bot

Link to image attribution

Main departure station: 350 S Illinois St

Union Station at 350 S Illinois St in Indianapolis is a major train and bus station which serves the Amtrak Cardinal, and bus carriers including Greyhound, Jefferson Lines, Miller Transportation, and Burlington Trailways. The modern station is located directly south of the historic 1888 Union Station, which now houses a hotel, several restaurants, and a wedding venue. Union Station is in the Wholesale District of downtown Indianapolis, within walking distance to eateries and hotels. There is even an underground, climate-controlled walkway from the station to the nearby Indiana Convention Center and Lucas Oil Stadium, home to the Indianapolis Colts.

All bus stations in Indianapolis:

  • 350 S Illinois St

Where does the bus arrive in St Louis?

Gateway Station - 430 S 15th St - STLAMT-0

Image credit: Chris Yunker

Link to image attribution

Main arrival station: Gateway Station - 430 S 15th St

Gateway Station opened in 2008 to consolidate St Louis’ transportation services into one central hub. The station’s award-winning design includes a pedestrian walkway with expansive colored glass windows overlooking the train tracks. Perfectly located in the heart of downtown St Louis, the station is surrounded by bars, restaurants, and hotels and is just a few blocks from Busch Stadium and the iconic Gateway Arch. Amenities inside the station include free Wifi, a food court, and a lounge for Amtrak’s First Class passengers. Gateway Station is a major stop for intercity bus service, several Amtrak train lines, and the city’s MetroLink which can connect you with the St Louis Lambert International Airport in just 30 minutes.

All bus stations in St Louis:

  • Gateway Station - 430 S 15th St

Need a return trip from St Louis to Indianapolis?

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