Cheap bus tickets from Indianapolis to St Louis
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Bus from Indianapolis to St Louis: Journey Information
There are 3 intercity buses per day from Indianapolis to St Louis. Traveling by bus from Indianapolis to St Louis usually takes around 4 hours and 28 minutes, but the fastest Greyhound bus can make the trip in 3 hours and 55 minutes.
| Distance | 230 mi (371 km) |
| Shortest duration | 3h 55m |
| Cheapest price | $32.98 |
| Trips per day | 3 |
| Most frequent service | Greyhound |
| Bus lines | 2 |
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Indianapolis to St Louis Bus Schedule

Bus Trip Reviews from Wanderu Customers
Average score for buses from Indianapolis to St Louis (Based on 2 ratings and reviews)
5.0
March 18, 2022 - Visiting family
Greyhound5.0
December 18, 2019 - Business
GreyhoundThere are several bus options that can take you from Indianapolis to St Louis:
See more detailsHow much is a bus ticket from Indianapolis to St Louis?
Bus tickets for a trip from Indianapolis to St Louis cost $34.31 on average. Opting to take a bus is a wallet-friendly way to make this trip. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Indianapolis to St Louis by travel date
If you're planning to travel by bus from Indianapolis to St Louis in the next month, the average ticket price is expected to range from $32 to $57. The cheapest bus tickets available in the next few weeks are for trips departing on September 15, 2026. If you’re looking to travel to St Louis this week, bus tickets are available starting at $35.
Average bus ticket prices from Indianapolis to St Louis by month
Taking the bus from Indianapolis to St Louis is usually cheapest in April, when the average ticket price is only $42. If you're planning to take the bus from Indianapolis to St Louis during September, keep in mind that bus ticket prices may be higher than usual, with an average price of $66. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 28 days in advance. This way, you can save up to $34.02 on your bus ticket compared to booking last-minute.
What bus companies travel from Indianapolis to St Louis?
There are multiple buses that travel from Indianapolis to St Louis, including Greyhound, FlixBus US. Here is what you should know about the 2 most popular bus lines:
| BUS | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 3 | 4h 27m | $50.10 |
| FlixBus US | 1 | 14h 40m | $95.97 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 3 bus trips from Indianapolis to St Louis every day, with the average journey taking around 4 hours and 27 minutes to complete. Bus tickets for Greyhound trips to St Louis usually start from $31.98.






FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Indianapolis to St Louis, and the average ticket for this route costs only $95.97.






Frequently asked questions about traveling by bus from Indianapolis to St Louis
There are 3 scheduled buses that travel from Indianapolis to St Louis every day, so you have a decent number of options to choose from. Furthermore, all of these are direct buses which you can take the entire route from Indianapolis to St Louis without transferring. Need more travel options? Consider taking the train from Indianapolis to St Louis; ticket prices start at $66.
TRIPS PER DAY
3
DIRECT TRIPS
3
The bus takes an average of 4 hours and 28 minutes to cover the 230 miles from Indianapolis to St Louis. However, the fastest bus only takes 3 hours and 55 minutes. In other words, you'll have plenty of time to rest and relax on the road. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
DISTANCE (MI)
230
DISTANCE (KM)
371
The first bus leaves at 4:50am and the last bus leaves at 7:55pm. To see the times for all buses from Indianapolis to St Louis, enter your specific travel dates in the search bar.
EARLIEST BUS
4:50am
LATEST BUS
7:55pm
Saturday is usually the day when buses are busiest, as many travelers take the bus to enjoy the weekend in St Louis. If you are planning to travel on a Saturday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Sunday is typically the least busy day for bus travel on this route. If you are looking for less crowded buses to St Louis, book your ticket for the last day of the week.
MOST CROWDED
Saturday
LEAST CROWDED
Sunday
City Information
Indianapolis



Indianapolis, or often referred to as just Indy, is the capital and largest city in the state of Indiana. While the city attracts thousands of visitors from the area every month, it is during Memorial Day weekend that Indianapolis becomes the place to be for over 300,000 race car fans from all over the globe. The reason for that is the Indianapolis 500, an annual automobile race and the world’s largest single day sporting event, taking place at the iconic Indianapolis Motor Speedway.
If you’re not in Indianapolis for Memorial Day weekend, you can learn about the race and see a rare collection of 500 Indy race vehicles and memorabilia at the Indianapolis Motor Speedway Museum. And while you’re on a history streak, stop by at one of the many war memorials found throughout the city, like the Soldiers and Sailors monument, the World War II memorial, and the Indiana War Memorial where you must check out the Shrine Room for a stunning one-of-a-kind experience.
Over the past few years, Indianapolis has also been cultivating a vibrant restaurant scene, offering classic American dishes made with ingredients from local farmers, and a growing selection of international cuisine. If you’re a beer fan, you will be happy to know that Indianapolis has some of the highest quality breweries in the U.S.
Located in the heart of America’s Midwest, Indianapolis offers easy connections by bus and train to other Midwestern hubs like Chicago, Louisville, and Cincinnati, while the conveniently located airport connects Indy with the rest of the world.
St Louis



St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.
Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.
Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.
The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.
Station Information
Where does the bus leave from in Indianapolis?
Main departure station: 350 S Illinois St

Union Station at 350 S Illinois St in Indianapolis is a major train and bus station which serves the Amtrak Cardinal, and bus carriers including Greyhound, Jefferson Lines, Miller Transportation, and Burlington Trailways. The modern station is located directly south of the historic 1888 Union Station, which now houses a hotel, several restaurants, and a wedding venue. Union Station is in the Wholesale District of downtown Indianapolis, within walking distance to eateries and hotels. There is even an underground, climate-controlled walkway from the station to the nearby Indiana Convention Center and Lucas Oil Stadium, home to the Indianapolis Colts.
All bus stations in Indianapolis:
- 350 S Illinois St
- Indianapolis (W Vermont St)
Where does the bus arrive in St Louis?
Main arrival station: Gateway Station - 430 S 15th St
All buses from Indianapolis arrive at one main station in St Louis.
All bus stations in St Louis:
- Gateway Station - 430 S 15th St
Need a return trip from St Louis to Indianapolis?
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