Cheap bus tickets from Indianapolis to Syracuse
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Indianapolis to Syracuse Bus Schedule
Is it better to travel by bus or train from Indianapolis to Syracuse?
There are usually 1 daily train trips available from Indianapolis to Syracuse.
Bus | Train | |
|---|---|---|
Avg. Price | Avg. Price$147.51 | Avg. Price$228.75 |
Daily Trips | Daily Trips3 | Daily Trips1 |
Duration | Duration22h 52m | Duration1d 3h 52m |
Bus from Indianapolis to Syracuse: Journey Information
There are 4 intercity buses per day from Indianapolis to Syracuse. Traveling by bus from Indianapolis to Syracuse usually takes around 22 hours and 55 minutes, but the fastest FlixBus US bus can make the trip in 19 hours and 10 minutes.
| Distance | 566 mi (910 km) |
| Shortest duration | 19h 10m |
| Cheapest price | $94.95 |
| Most frequent service | FlixBus US |
| Bus lines | 2 |

What bus companies travel from Indianapolis to Syracuse?
There are two bus lines that have daily service from Indianapolis to Syracuse that you can compare and book on Wanderu. Of these two carriers, FlixBus US usually offers more choice, with 3 scheduled trips per day.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 3 | 21h 4m | $196.22 |
| Greyhound | 1 | 1d 0h 11m | $165.31 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 3 trips per day from Indianapolis to Syracuse, and the average ticket for this route costs only .
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 1 bus trips from Indianapolis to Syracuse every day, with the average journey taking around 24 hours and 11 minutes to complete. Bus tickets for Greyhound trips to Syracuse usually start from $96.
Frequently asked questions about traveling by bus from Indianapolis to Syracuse
The bus takes an average of 22 hours and 55 minutes to cover the 566 miles from Indianapolis to Syracuse. However, the fastest bus only takes 19 hours and 10 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Saturday is usually the day when buses are busiest, as many travelers take the bus to enjoy the weekend in Syracuse. If you are planning to travel on a Saturday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.
The first bus leaves at 12:00am and the last bus leaves at 11:00pm. To see the times for all buses from Indianapolis to Syracuse, enter your specific travel dates in the search bar.
There are 4 scheduled buses that travel from Indianapolis to Syracuse every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey.
Need more travel options? Consider taking the train from Indianapolis to Syracuse; ticket prices start at $144.00.
City Information
Indianapolis



Indianapolis, or often referred to as just Indy, is the capital and largest city in the state of Indiana. While the city attracts thousands of visitors from the area every month, it is during Memorial Day weekend that Indianapolis becomes the place to be for over 300,000 race car fans from all over the globe. The reason for that is the Indianapolis 500, an annual automobile race and the world’s largest single day sporting event, taking place at the iconic Indianapolis Motor Speedway.
If you’re not in Indianapolis for Memorial Day weekend, you can learn about the race and see a rare collection of 500 Indy race vehicles and memorabilia at the Indianapolis Motor Speedway Museum. And while you’re on a history streak, stop by at one of the many war memorials found throughout the city, like the Soldiers and Sailors monument, the World War II memorial, and the Indiana War Memorial where you must check out the Shrine Room for a stunning one-of-a-kind experience.
Over the past few years, Indianapolis has also been cultivating a vibrant restaurant scene, offering classic American dishes made with ingredients from local farmers, and a growing selection of international cuisine. If you’re a beer fan, you will be happy to know that Indianapolis has some of the highest quality breweries in the U.S.
Located in the heart of America’s Midwest, Indianapolis offers easy connections by bus and train to other Midwestern hubs like Chicago, Louisville, and Cincinnati, while the conveniently located airport connects Indy with the rest of the world.
Syracuse
Syracuse might not be the top destination for tourists in New York, but it does have plenty of quirky and fun destinations for all age groups. Upon your first arrival to the city, don’t miss out on the chance to take a stroll around the historic Armory Square, considered to be the top destination by locals. The square also features plenty of restaurants and nightclubs if you are looking for the quarter with the best nightlife in town. If you want to mingle with a good crowd for some fun, the Carrier Dome, which is located within the campus of Syracuse University, will offer the adrenaline rush you need. For those seeking a more culturally-inclined activity, head towards the Everson Museum of Art and marvel at the most significant collection of American ceramics in the country.
Syracuse features a vibrant and diverse food scene. If you enjoy brunch, Modern Malt, a local favorite, is the place to be. And for some amazing authentic Cuban dishes, head to Esquina Habanera.
The busiest bus and train station in the city is the William F. Walsh Regional Transportation Center. From there you can catch an Amtrak train or a bus run by Greyhound, New York Trailways, OurBus or Jefferson Lines to various cities, including New York, Boston, and Albany. Syracuse is served by Amtrak’s Empire Service, Lake Shore Limited and Maple Leaf lines. The Syracuse Hancock International Airport is the principal airport in the city, and it is located five miles northwest of downtown.
Station Information
Where does the bus leave from in Indianapolis?
Main departure station: E Washington St
Indianapolis has two bus stations with service to Syracuse.
All bus stations in Indianapolis:
E Washington St
350 S Illinois St
Where does the bus arrive in Syracuse?
Main arrival station: 1 Walsh Circle Ste 30
All buses from Indianapolis arrive at one main station in Syracuse.
All bus stations in Syracuse:
1 Walsh Circle Ste 30
Get around town with Moovit
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